Pregabalin is an anticonvulsant, anxiolytic, and analgesic medication used to treat epilepsy, neuropathic pain, fibromyalgia, opioid withdrawal, restless leg syndrome, and generalized anxiety disorder. Pregabalin is also safe to use in the treatment of postherpetic neuralgia.

Pregabalin was approved for medical use in the U.S. in 2004 and is a Schedule V controlled substance. According to demographic data, Pregabalin was the 78th most commonly prescribed in the U.S. in 2020, with around 10 million prescriptions. The drug is mainly found under the brand name Lyrica but can also be found in less popular brands.

Pregabalin can also be classified as a Gabapentinoid that blocks subunits containing calcium channels. Pregabalin inhibits calcium channels, leading to a slower release of excitatory neurotransmissions. Pregabalin may also be able to transport amino acids and modulate potassium channels.

What is Pregabalin used for?

Pregabalin tablets are commonly used to relieve pain that occurs in arms, fingers, hands, toes, feet, or legs in diabetic or postherpetic neuralgia (PHN) patients. Pregabalin is one of the prescription drugs commonly used to treat pain that can happen due to spinal cord injury or seizures. It is considered one of the best anticonvulsants available in independent pharmacies after approval by the FDA.

The tablet is used for the following health issues:

• Fibromyalgia (muscular pain, changes in mood, sleep complications, and fatigue)
• Any pain from shingles, diabetes, or spinal cord injury.

Unofficial or off-label uses may include:

• Anxiety
• Back pain
• Migraines

Can I buy Pregabalin online?

Yes, you can buy Pregabalin online through Medambien. You simply have to place an order, and after confirmation, Pregabalin will be sent to your address quickly in discreet packaging. For any further details, you can contact us at: contact@medambien.com

How effective is Pregabalin?

The effectiveness of Pregabalin may vary from condition to condition for which the medication is being used.

• For epileptic seizures, Pregabalin may be able to reduce the effects for most patients. Depending upon the intensity of the seizure, most patients can reduce effects by 50% after taking Lyrica.
• For fibromyalgia, Pregabalin has helped improve quality of life by improving sleep patterns and reducing musculoskeletal pain.
• For neuralgia, Pregabalin has been an effective form of medication. Be it diabetic neuropathy, postherpetic neuralgia, or central nerve pain, Pregabalin is a reliable form of treatment.

How should Pregabalin be taken?

You can take Pregabalin in the form of a tablet or syrup. Either way, consuming the drug with or without food is safe. However, the ideal time to take Pregabalin is after an evening meal. The per-day dosage can be divided into two to three doses depending on one's preference and doctor's prescription.

You should swallow the Pregabaline tablet directly with water. The tablet should not be broken or crushed for consumption. In the case of the syrup, measure the liquid using a medicine cup or spoon. Avoid Pregabalin if you are allergic to its ingredients, as it may cause serious allergic reaction.

What dose of Pregabalin should be taken?

Pregabalin comes in various strengths, and the dose of the medicine may vary from person to person, depending on one's strength, tolerance, and medical condition. Seeking medical assistance by consulting a healthcare professional on your dosage is the best option to prevent any adverse side effects.

Dose for onset seizures

• Adult dosage (18 to 64 years) varies from a usual dose of 150mg daily to the maximum dosage limit of 600mg in 2 to 3 divided doses.
• Pediatric dosage (4 to 17 years) varies according to age and weight. For children weighing from 11 to 30kg, 3.5mg/kg can be divided throughout the day, whereas, for children weighing 30kg or more, 2.5mg/kg can be divided throughout the day. The maximum dose should not exceed 10 mg/kg (600mg) a day.
• Senior dosage (65 years and above) depends on the medical condition and history of the individual patient.

Dose for fibromyalgia

• Adult dosage (18 to 64 years) varies from a standard dose of 75mg twice daily to 450mg maximum.
• Senior dosage (65 years and above) depends on the individual patient's medical condition, body reaction, and history.

Dose for neuropathic pain

• Adult dosage (18 to 64 years) from a regular dose of 75mg twice daily to 600mg maximum.
• Senior dosage (65 years and above) depends on the medical condition and history of the individual patient. However, doses are lower as compared to an average adult.

Dose for diabetic peripheral neuropathy

• Adult dosage (18 to 64 years) from a regular dose of 50mg thrice a day to 300mg maximum.
• Senior dosage (65 years and above) depends on the medical condition and history of the individual patient. The dosage has more to do with the tolerance of the individual.

Patients with pre-existing liver or kidney problems and breathing problems should consult their doctor before taking Lyrica. Pregabalin may cause heart problems in patients with diabetic neuropathy.

Why is Pregabalin considered a good treatment for pain relief?

Pregabalin is considered one of the best treatments for pain relief because it has little or no significant adverse effects and offers management of severe nerve pain. The medication is extraordinarily efficacious as it controls seizure activity. Moreover, Pregabalin may also help children who suffer from partial seizures.

Even the off-label benefits of the drug are impressive. Pregabalin helps manage anxiety, back pains, and alcohol withdrawal symptoms.

What are the side effects of Pregabalin?

Although Pregabalin is considered a safe drug for pain management, some common side effects exist that 10% of users may experience. Slightly severe side effects were only found in users taking Lyrica non-suitable dosages or ignoring a contraindicated state. Therefore, staying in touch with your medical expert is always advisable; you get help when needed.

Common side effects:

• Nausea
• Headaches
• Sleepiness
• Blurry vision
• Dizziness
• Weight gain
• Trouble concentrating
• Fever
• Dry mouth
• Upset Stomach
• Constipation

Severe side effects:

• Allergic reactions (skin redness or rash, swelling of tongue, throat, etc.)
• suicidal thoughts
• Eye problems
• Fluid retention
• Irregular heartbeat

FDA warns that Pregabalin may cause breathing problems in patients with respiratory risk factors. Contact your doctor immediately if you experience trouble breathing or an allergic reaction, and stop taking Lyrica. With proper preventative measures, side effects can be avoidable in most cases. However, lingering side effects may require the help of a medical expert.

Can I take Pregabalin with alcohol?

Avoid taking alcohol with Pregabalin. Mixing both can cause difficulty concentrating, dizziness, and drowsiness. Some may even experience impaired thinking and judgment.

Pregabalin and pregnancy:

Taking Lyrica during pregnancy may increase the chance of congenital disabilities in the baby. Do not start or stop taking Pregabalin or other medications if you become pregnant while taking them before consulting your doctor.

If you are taking Pregabalin for epilepsy, it must be well treated during pregnancy, as seizures can harm both the mother and the baby. The doctor may recommend folic acid as it helps the baby to grow normally.

Pregabalin and breastfeeding:

Pregabalin passes into breast milk in very small amounts and is unlikely to cause any side effects. If your baby is healthy, the doctor will let you take Pregabalin, but consultation is essential.

While taking Pregabalin, keep an observation if your baby is feeding well, does not seem unusually sleepy, or shows any other changes that may pose a concern.

Alternate treatment options for seizures or pain relief

Some alternate treatment options for Pregabalin include:

• Cymbalta
• Gabapentin
• Tramadol